Aspects of Steroids

Endocrine aspects of anabolic steroids.

Understanding of the mechanism of androgen action has been enhanced by advances in knowledge on the molecular basis of activation of the androgen receptor and the importance of tissue conversion of circulating testosterone to dihydrotestosterone and estradiol. New evidence supports the view that supraphysiological doses of anabolic steroids do have a definite, positive effect on muscle size and...

Clinical aspects of patients with sarcoglycanopathies under steroids therapy.

UNLABELLED Patients with sarcoglycanopathies, which comprise four subtypes of autosomal recessive limb-girdle muscular dystrophies, usually present with progressive weakness leading to early loss of ambulation and premature death, and no effective treatment is currently available. OBJECTIVE To present clinical aspects and outcomes of six children with sarcoglycanopathies treated with steroids...

Steroids and Related Compounds: Basic and Clinical Aspects

1 Departamento de Bioquímica, Universidade Federal de Santa Catarina, Caixa Postal 5069, 88040-970 Florianópolis, SC, Brazil Health Sciences Area, Universidade Comunitária da Região de Chapecó, Avenida Senador Attílio Fontana 591E, 89809-000 Chapecó, SC, Brazil 3 Department of Environmental and Occupational Medicine, Robert Wood Johnson Medical School, University of Medicine & Dentistry of New ...

Psychoneuroendocrine aspects of temporolimbic epilepsy. Part II: Epilepsy and reproductive steroids.

Reproductive dysfunction is unusually common among men and women with epilepsy. Reproductive endocrine disorders are also common and may be causal. The association between particular reproductive endocrine disorders and the laterality and focality of epileptiform discharges suggests an etiologic role for epilepsy. Gonadal steroids are neuroactive and influence seizure occurrence: estrogen is ep...

MEDICAL ASPECTS OF ISLAMIC FASTING